NIHR Maudsley BRC Blog

Our latest news and events

Molecular ageing clocks – making the links between mental illness and shorter lifespans

Dr Julian Mutz is a post-doctoral research associate at the Social, Genetic and Developmental Psychiatry (SGDP) Centre at the Institute of Psychiatry, Psychology & Neuroscience. Cathryn Lewis is Professor of Genetic Epidemiology & Statistics at King’s College London and NIHR Maudsley BRC’s deputy theme lead for Trials, Genomics and Prediction.

In this blog, they discuss their research on biological ageing in individuals with mental health conditions and highlight how their epidemiological studies may inform clinical research and practice.

By NIHR Maudsley BRC at 4 May 2023

Diagnosis of a genetic cause in hundreds of people with motor neuron disease could be missed due to “arbitrary age limits and rules” on genetic testing, new study shows

Based on the findings of a new study published in Brain, researchers from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London are calling for a complete rethink of the national guidelines surrounding who can access genetic testing for amyotrophic lateral sclerosis (ALS), also called motor neuron disease.

By NIHR Maudsley BRC at 27 Sep 2022

New research suggests a causal link between blood group and severe COVID-19

A new study has analysed over 3000 proteins to identify which are causally linked to the development of severe COVID-19. This is the first study to assess such a large number of proteins for their connection to COVID-19. The findings provide insight into potential new targets for approaches to treat and prevent severe COVID-19.

 

By NIHR Maudsley BRC at 3 Mar 2022

Genetics helps estimate the risk of disease – but how much does it really tell us?

Genetics research has made momentous strides in the 21st century. At the start of the century, we had a broad understanding that most medical problems in the developed world are partly genetically determined but lacked the technology to fully explore the secrets hiding in our genome.

 

By NIHR Maudsley BRC at 26 Jan 2022

Bringing together imaging and genetic mapping to investigate patterns of vulnerability in the brain

Dr Daniel Martins is a Clinical Research Associate, Dr Mattia Veronese is a senior molecular imaging scientist and Dr. Ottavia Dipasquale is a Research Associate, all in the Department of Neuroimaging at King’s College London. In this blog they discuss their recent study which is funded by the NIHR Maudsley BRC and has brought together scientists from across the world to define a new approach to integrate neuroimaging and a form of genetic mapping.

By NIHR Maudsley BRC at 21 Jan 2022