- NIHR Maudsley BRC
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- NIHR Wellcome King's Clinical Research Facility
- NIHR King's Clinical Research Facility
- Eleanor Sherwood
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- South London and Maudsley NHS Foundation Trust (15)
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- COVID19 (2)
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- Precision Psychiatry (2)
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- Vaccine (1)
- King's Health Partners (1)
- MRI (1)
- Rett syndrome (1)
- UK Disability HIstory Month (1)
- New study demonstrates link between brain chemical and visual processing in autism
- Psilocybin, in 10mg or 25mg doses, has no detrimental effects in healthy people
- No convincing scientific evidence that hangover cures work, according to new research
- Applications invited for Equality, Diversity & Inclusion Champion role
- Next generation of rapid-acting antidepressants: Can ketamine help prevent suicide?
- New collaboration with digital therapeutics company to investigate preventable opioid respiratory deaths
- Bringing together imaging and genetic mapping to investigate patterns of vulnerability in the brain
- Love Your Liver Month
- Genetics helps estimate the risk of disease – but how much does it really tell us?
- Fellows award for Dr Katherine Young for work on the mental health of young people during and after the pandemic
- NEWS2 evaluated for prediction of severe COVID-19 outcome in large international study
- SIREN study finds past COVID-19 infection provides some immunity for at least five months
- Interview with Miguel Vasconcelos Da Silva
- COVID-19 lockdown loneliness linked to more depressive symptoms in older adults
- The significant effect of lockdown on gambler’s mental health
- Antibiotic may improve outcomes for depression in people with low level inflammation
- Novavax trial reveals 89.3% effectiveness in preventing COVID-19
- Case studies
- Deciphering the genetics behind eating disorders
- NIHR appoints Senior Investigators for 2021
- Depression and anxiety are associated with disagreement between patient and doctor assessments of psoriasis severity.
- Professor Peter Goadsby awarded world’s top Brain Prize 2021
- Interview with Dr Parisa Mansoori
- New study highlights the urgent need to reduce inflammation in overweight people with depression
- Novavax confirms vaccine provides 100% protection against severe COVID-19
- NIHR welcomes new vision for the Future of UK Clinical Research Delivery
- COVID-19 pandemic leads to rapid uptake of remote consultations in mental healthcare
- An Interview with Chifundo Stubbs
- Brain scans could offer sign of postpartum psychosis risk
- Innovative UK data hub to enable research and innovation to tackle mental illness
- Inflammation is a core feature of depression: new evidence from large-scale study
- Mothers’ depression impacts mother-infant relationships
- Shifts to remote mental health services continued after lockdown, according to new study
- An interview with Zunera Khan
- Silent MRI: improving access to neuroimaging research
- Simple blood test can accurately reveal underlying neurodegeneration, according to new research
- New research from King's has identified three key inflammatory proteins which are lower in individuals at risk of severe COVID-19.
- New insight into how anti-inflammatory effects of omega-3 fatty acids could help reduce depression
- Five ways universities could improve mental health support for male students
- CogStack wins an Artificial Intelligence in Health and Care Award
- Volunteer calls for others to support dementia research in south London
- Europe's first 'game-changing' portable MRI machine arrives at King's Health Partners
- Global ALS/MND recognition Day
- Multiple long-term physical health problems increase risk of depression later in life
- An interview with Dr Marija-Magdalena Petrinovic
- COVID-19 variant vaccine begins recruiting in south London
- New Race and Ethnicity Advisory (READ) group is recruiting members
- NIHR Fellowship awarded to Dr Brendon Stubbs for research in persistent pain and serious mental illness
- Knowing what we don’t know: How statistics can help autistic people to live their best life
- New funding for innovative neuroimaging research
- Words don’t come easy: identifying perinatal self-harm in healthcare records
- Problems in thinking and attention linked to COVID-19 infection
- Opportunity for researchers to consult with new Race and Ethnicity Advisory group
- Exposure to air pollution linked with increased mental health service-use, new study finds
- Maudsley Hospital and King’s College London’s National Addiction Centre light up purple to raise awareness for International Overdose Awareness Day
- An interview with Charles Curtis
- Join our Adolescent Mental Health Advisory Group
- Common factors within the gut associated with depression and bipolar disorder
- SURE Recovery App – two years on after its launch
- Using CRIS to map the impact of the COVID-19 pandemic – service user and carer priorities
- Genetic risks for depression differ between East Asian and European groups
- Excess deaths in people with mental health conditions increased during the COVID-19 pandemic
- ADHD Awareness Month: Developing neurofeedback as a new treatment for ADHD
- Genetic risk of mental health conditions may influence where people choose to live, study suggests
- Eating disorders are just as likely to start in adulthood as childhood, report finds
- An interview with Dr Charlotte Tye
- NIHR: Your Path in Research
- Rett Syndrome Awareness Month
- Using MRI to investigate the brain response to inflammatory stimuli
- MANTRA training developed at SLaM to be rolled out to adult eating disorder services across the UK
- Six years of memory decline seen in anxious, depressed older people during pandemic
- An interview with Dr Katherine Young
- The silent and widely impacting cost of Vulvodynia: lessons learned and future recommendations
- What can research tell us about engaging adolescent boys into school-based mental health workshops?
- Diagnosis of depression in adolescents can negatively impact educational performance, study shows
- Using neurofeedback as a means of treating feelings of self-blame in depression
- Review looks at benefits and barriers following shift to remote mental health services during pandemic
- What is treatment-resistant depression? New report calls for clearer definition to inform research and improve treatment
- NIHR Maudsley BRC: A Year in Review 2021
- UK Disability History Month - an interview with Naomi
- People feel lonelier in crowded cities – but green spaces can help
- Vitamin D supplementation does not improve symptoms in people with psychosis, study finds
- BRC researchers on the Highly Cited list doubles to twenty
- CRIS Blog: Are we under-estimating self-harm rates due to differences in hospital admittance procedures?
- BRC Researchers celebrated at the King’s Awards
- New study finds evidence for reduced brain connections in schizophrenia
- Exposure to trauma ‘activates’ genes into causing depression
- Nurses in research blog: Emma and Naomi
- New findings on the effects of cannabidiol on people with psychosis
- New centre of excellence for children and young people's mental health launched
- High volumes of mental health-related tweets associated with crisis referrals
- Call opens to drive the future of health data research
- CRIS Blog: Answering real-world questions about medication and mental health through pharmacoepidemiology
- CRIS Blog: Appropriate use of healthcare records for research
- CRIS Blog: Artificial Intelligence and Data in Suicide Prevention
- Largest ever study of eating disorders launches in England
- C4C research register now totals 20,000 people
- Georgia’s research secondment
- Study finds that Community Treatment Orders do not reduce hospital readmission rates or stays
- 10,000 people could benefit from new migraine drug
- Thirty risk factors found during and after pregnancy for children developing psychosis
- Heroin injection associated with respiratory disorder
- Researchers appeal to public for help to assess mental health impact of the COVID-19 pandemic
- CRIS Blog: CRIS in the time of coronavirus
- Depression and anxiety increase premature death by up to 134%
- Mental health and brain research must be a higher priority in global response to tackle COVID-19 pandemic
- Stories from our students: Becki
- COPE Study: Investigating the impact of the COVID-19 pandemic on mental health and well-being
- Thought provoking men’s mental health film released
- Animated parenting tips for struggling households
- Researchers track COVID-19 isolation effects on older people’s health and wellbeing
- From Babylonian blood-letting practices to wearable tech, new film on the evolution of depression perceptions and treatment
- Patient and public recommendations for getting involved in BRC research
- Cognitive behavioural therapy reduces the impact of dissociative seizures
- Mind the Gap 17-25: A diagnosis doesn’t define you
- Sarah Markham writes about her experiences in research
- Covid-19 Psychiatry and Neurological Genetics (COPING) study
- Trial testing a unique formulation of ibuprofen to treat COVID-19 launches
- New study to monitor the real-time effect of COVID-19 on mental health services
- Introducing the CRIS Natural Language Processing (NLP) Service
- Study shows Cognitive Remediation Therapy leads to improvement in cognitive skills and well-being in people with bipolar disorder
- New Research Training and Capacity Development lead announced
- Growing numbers of alcohol related hospital admissions linked to local spending cuts
- ACE inhibitors and ARBs not associated with severity of Coronavirus
- Data linkages animation explores the evolution of healthcare records in research
- Study estimates impact of COVID-19 pandemic on UK mental health after first month of lockdown
- Genes related to inflammation and stress may help tailor treatments for depression
- Can wearables like Fitbit devices be used to help detect COVID-19?
- Lithium in drinking water linked with lower suicide rates
- Loss of potential: teens diagnosed with depression show reduction in educational achievement from primary school to GCSE
- £1.2 million to roll-out dementia care home programme to COVID-hit sector
- NIHR announces mental health research goals for next decade
- Rosalind helps researchers navigate personal health data
- An interview with Dr Ndaba Mazibuko
- National study into neurological impact of COVID-19
- Study supports link between traffic-related air pollution and mental disorders
- How our eLIXIR research database helps reduce risk of health problems in mothers and children
- Eating a healthy diet can ease symptoms of depression
- CRIS Blog: Pathfinders and the public
- NIHR Maudsley BRC researchers host dementia discussion in collaboration with South London Theatre
- Could intranasal oxytocin be used to treat people at clinically high risk of psychosis?
- CRIS blog: Using data on hospital episodes to look at the physical health of people with personality disorders
- Cannabis-based medicine to be tested in Alzheimer's trial
- Largest ever study of depression and anxiety now recruiting individuals from Northern Ireland, Scotland, and Wales
- One in ten UK hospital inpatients is alcohol dependent
- CRIS Blog: Art and Value at Bethlem Gallery: an art-science collaboration with Sarah Carpenter and CRIS
- Genetic study reveals metabolic origins of anorexia
- Compensatory strategies to disguise autism spectrum disorder may delay diagnosis and have negative consequences for mental health
- Close monitoring essential to ensure safety of ketamine for depression
- Six BRC academics promoted to new positions, including two new professorships
- CRIS Blog: Medichec - A tool to make prescribing safer for people with dementia
- Study gets under way to test psilocybin for treatment-resistant depression
- 'An inspiring day': BRC community gathers to share knowledge at conference
- CRIS Blog: CRIS data demonstrates need for better physical healthcare for people who use heroin
- SURE Recovery: the new addiction recovery app designed alongside service users
- Our first ever artist residency to kick off with Afrobeat and Dub gig in South London
- Expert panel examines barriers faced by working class academics
- UK Biobank mental health study
- CRIS blog: Using CRIS to evaluate mental health diagnoses in routine national statistics
- Engaging in physical activity decreases people’s chance of developing depression
- Unprecedented study identifies 44 genetic risk factors for major depression
- New research: Hospitals often missing dementia despite prior diagnosis
- 2018 Takeover Challenge
- CRIS blog: The future of psychiatry research
- CRIS blog: Do long-term prescriptions of multiple antipsychotics contribute to the reduced life expectancy of patients with serious mental illness?
- Improving dementia care and treatment saves thousands of pounds in care homes
- New service in south London reduces hospital readmissions for people with bipolar disorder
- Ten BRC researchers and academics among most cited in the world
- Students 'take over' the BRC
- Computers can ‘spot the difference’ between healthy brains and the brains of people with Dissociative Identity Disorder
- Service User Advisory Group for 12-16-year-olds
- New Clinical Disorders and Health Behaviours cluster lead announced
- Blog: The SLG Arts Assassins collaborate with the BRC
- Professor Matthew Hotopf receives CBE at Buckingham Palace
- Professor Robert Stewart awarded ‘Collaborate to Innovate’ project
- NIHR Maudsley BRC researchers receive Senior Investigator awards
- Research blog: Using social media to recognise mental health conditions
- Department of Health Chief Scientific Adviser Chris Whitty visits Maudsley BRC
- NIHR Maudsley BRC commences five-year research programme
- IMPARTS Seminar Learning from experience
- New research highlights higher hospitalisation rates in people with intellectual disabilities
- Digital Technology for Mental Health: Asking the right questions
- Maudsley becomes London’s Global Digital Exemplar
- CRIS blog: An online risk calculator to identify candidates for early intervention services
- NIHR Maudsley BRC researcher wins award to understand suicide warning signs in children
- Who are the NIHR? #WeAreNIHR
- Brain stimulation may improve cognitive performance in people with schizophrenia
- Risk for bipolar disorder associated with faster ageing
- Omega-3 fatty acids improve symptoms in children and adolescents with ADHD
- South London and Maudsley tops NIHR league table for number of active research studies
- Connecting care homes with research
- Research blog: Using advanced search technologies to help manage infectious disease outbreaks
- A&E attendance for people with dementia is common and increasing
- Event: Seminar on dementia art project "Beyond Memories"
- Professor Oliver Howes receives Royal College of Psychiatrists Award
- First network analysis of patient flow in two UK hospitals published
- Honorary Degree for Professor Dame Til Wykes
- Concentrated naloxone nasal spray as good as injection
- Professor Matthew Hotopf appointed Vice Dean
- Potential for machine learning to predict unknown adverse drug reactions
- Complications at birth associated with lasting chemical changes in the brain
- Study examines opiate-dependent patient deaths
- NIHR Lectureship awarded
- Treatment cuts migraine days by half
- CRIS Blog: Serious Mental Illness and Pregnancy
- Kings world-class contribution to understanding of clozapine
- Research blog: PROMPT project reveals complex profile of people using psychological therapy services
- Tony David John Toulmin Lecture
- Crick synapse event
- IMPARTS Seminar Harnessing digital technology in mental and physical healthcare
- CRIS blog: Eight years on
- Experts call for greater recognition of little-known forms of dementia
- Event: Clinical Research Facility Research Forum
- Ewan Birney MRC SGDP Seminar
- Al Chalabi Sheila Essey Award
- Event Pint of Science 2016
- RADAR CNS smartphone wearable devices transform medical care
- Cardiovascular drug underprescribing
- Consultation reveals better integration between physical & mental health physicians as top priority
- Prestigious Fellowships awarded to BRC researchers
- Dermatology clinic psychology screening project shortlisted for BMJ Awards
- Independent Researcher Awards 2016
- BMJ Award for team who are incorporating mental health service into dermatology clinic
- Research blog systematic biases in death certification
- Event launch of new collaboration for digital innovation in mental health
- Victoria Derbyshire show inheritance mental illness
- BRC spin out Mindwave launches
- Research blog: Learning how to be a critical friend to researchers
- Research blog International Clinical Trials Day
- Blood test to personalise depression treatment for the first time
- Centre for Translational Informatics launches
- Professor John Strang receives Knighthood
- Film mental health summer school
- Mental health hackday - your help needed
- Research blog: Trialling an online tool to help women make decisions about antidepressants in pregnancy
- Data linkage group your help needed
- CRIS blog: Investigating the impact of antipsychotic medications used to treat people with serious mental illness
- Research blog Maudsley BRC part of winning team at NIHR training camp
- Neuroimaging theme research funding
- NIHR Maudsley BRC announces 2016 Youth Awards winners
- Event: Illusions A window to your brain
- Matthew Hotopf wins prestigious Katon Research Award
- IMPARTS shortlisted for HSJ award
- NIHR Maudsley BRC receives £66m new investment from government
- NIHR Maudsley BRC researchers win prestigious awards
- Event NIHR i4i Programme Mental Health Challenge Awards Launch
- Genetic tests could help predict which psychosis patients will develop schizophrenia
- BRC leaders receive academic promotions
- Event No Exchange, Same Pain, No Gain - Risk-Reward of Wearable Healthcare Disclosure for Receiving Pain Treatment
- C4C recruits 10k
- Research blog: How fatty clues in the blood are improving our understanding of Alzheimer’s disease
- Early intervention shows promising long-term reduction in severity of autism symptoms
- Bringing mental health education to a classroom of 300
- South London and Maudsley rated top mental health trust for recruiting patients to clinical studies
- Mental Health & Technology: Ideas Generation Workshop
- NIHR i4i mental health challenge launch
- UK Government announces £4m investment in NIHR Wellcome Trust King’s Clinical Research Facility
- NIHR Maudsley BRC PhD student wins International Society for the History of Neurosciences book prize
- NIHR Maudsley BRC's takeover challenge
- Event Suicide detection and prevention using mobile technology, social media and informatics
- Event Misconceptions and Reconceptualisations in Digital Mental Health
- Research blog: Defining treatment resistance in schizophrenia
- Mental health needs of baby boomers covered in new report from England’s Chief Medical Officer
An interview with Dr Ndaba Mazibuko: on Covid-19 therapeutic clinical trials, working with patients and running on Hampstead Heath
Dr Ndaba Mazibuko, is a Clinical Research Fellow and a Study Clinician at the Centre for Neuroimaging Sciences and the Repurposing Lead at the Centre for Innovative Therapeutics (C-FIT), Institute of Psychiatry, Psychology & Neuroscience at King’s College London.
The C-FIT is a partnership between King’s College London’s Institute of Psychiatry, Psychology & Neuroscience and South London and Maudsley and King’s College Hospital NHS Foundation Trusts. It exists to support commercial companies and world-leading academics to collaborate more effectively.
Please can you give us an overview of your role(s)?
I work as a study clinician across a number of clinical trials in the Psychiatry / Neuroscience space. The studies are often unified by Neuroimaging, I’m the resident clinician within the Centre for Neuroimaging Sciences. I provide the clinical oversight for the suitability of patients to take part in these studies and I monitor the safety and wellbeing of these participants while providing an environment that allows for the collection of the most robust and meaningful data possible.
My C-FIT role has a focus on Drug Repurposing. This is the practice of identifying new uses for existing approved drugs that are outside the scope of the original disease indication. This increasingly explored strategy has the advantage of allowing faster and cheaper delivery of medicines to patients. Crucially, it is also a pathway to supporting Healthcare systems such as the NHS which are increasingly overburdened with the cost of new drugs. My C-FIT work includes connecting with other investigators or stakeholders involved in Drug Repurposing to explore the most efficient ways of moving this approach forward.
What are the favourite parts of your role?
I enjoy the interaction with patients, it’s a reminder of why we do what we do, seeing the real world issues that can be or have been enhanced by research is inspiring and a good focus for keeping ideas relevant.
Are there any aspects of your role which would surprise someone to know?
The aspect of my role that might be less obvious is emphasis on communication and interpersonal skills. Designing and implementing research requires a healthy dose of peer and participant engagement. Communicating well with (including listening well to) study patients and participants is an essential approach to conducting research that will achieve the highest public utility and patient benefit.
Can you give a brief overview of your career? What are you most proud of?
Prior to my current position I worked as a Neurology and Acute Stroke Registrar at King's College Hospital. I have several years’ experience as a clinician in varied disciplines within the NHS in addition to clinical experience in Australia (where I trained) and also in Africa.
I’m proud of the fact that, through the support and inspiration of many people along the way, I’ve managed to navigate a journey from a small town in a remote part of Botswana to enjoying a career in a global centre of excellence, a centre with a collaborative, international approach.
I’m also proud to work with a team and an organisation that is passionate about providing the space for patient focused innovative research.
How did you get interested in research?
My interest in research was driven by the opportunity to contribute pro-actively and creatively to attempts to find patient focused solutions to the healthcare problems. Clinical work is often too busy with delivery of much needed service, it doesn’t regularly afford the time to explore ways to refine or enhance practice, research can offer that space.
How has the Covid-19 pandemic impacted your work?
Covid-19 has impacted my work significantly. In 2020 I was an investigator on a Covid-19 therapeutic clinical trial called the LIBERATE Trial – an anti-inflammatory agent which is also an example of the utility of Drug Repurposing.
In addition to this, I was also working on a protocol and implementation plan for a COVID-19 rapid antibody prevalence study.
I also went in to help out for a few on-call shifts as a medic with the acute medicine teams on the KCH COVID-19 and general medical wards at the height of the second wave in January / February this year.
What does an average working day look like for you?
At the moment an average day is filled with virtual meetings and study related document writing. Pre-pandemic I spent much of the average day working with patients or healthy volunteers ensuring their suitability and safety for inclusion in the clinical trial process. There is a lot of time spent in conversation with collaborators and participants.
What are you working on at the moment?
I am currently working with a team to provide clinical assessment and monitoring on an interesting neuroimaging study investigating the mechanisms of a possible treatment for Parkinson's Disease Psychosis.
I'm also working with a group on a study that is about to start recruiting patients who have a treatment resistant depression. This exciting new study will explore the effects on ketamine on brain physiology and how that relates to the clinical symptom response that these patients might experience after receiving this drug.
Favourite TV series?
'The Wire'. Or something more recent that stands out is the ‘Chernobyl’ series.
What is your go-to karaoke song?
Technically this is a go-to dance track - Whitney Houston’s 'I wanna Dance with Somebody' but I will go with this as there’s usually “singing” involved.
Who is your science hero?
I’m not sure I have a particular science hero, but Isaac Newton is an example of a scientist I find interesting. The breadth (and multidisciplinary nature) of his work is fascinating. And the courage to challenge even the most accepted or established ideas.
Best discovery of lock down
I live close to Hampstead Heath, so was somewhat familiar with it already but I feel like I’ve got to discover and enjoy much more of it in the last few months. That, and the perhaps the not so surprising “discovery” of banana bread making.
How would you spend your perfect Saturday?
A run around (some of) the Heath, followed by a delicious brunch, perhaps a play or a film screening with Q&A and post film debrief drinks with friends.
Tags: Neuroimaging - Covid-19 - BRC Interview Series - Patient and Carer Involvement and Engagement -
By NIHR Maudsley BRC at 14 Oct 2020, 13:00 PM
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