Novavax trial reveals 89.3% effectiveness in preventing COVID-19

Interim analysis of study shows that the NIHR-supported Novavax COVID-19 vaccine is 89.3% effective at preventing COVID-19, including effectiveness against the new variants of concern.

By NIHR Wellcome King's Clinical Research Facility at 29 Jan 2021

Antibiotic may improve outcomes for depression in people with low level inflammation

King’s College London researchers have found evidence that minocycline, a widely used antibiotic with anti-inflammatory properties, gave greater improvement in depressive symptoms in patients with treatment resistant depression with low-grade peripheral inflammation.

 

By NIHR Maudsley BRC at 28 Jan 2021

The significant effect of lockdown on gambler’s mental health

King’s College London study assesses the potential impacts of COVID-19 nationwide lockdown on longer term depression, anxiety, and stress in gamblers in the UK.

 

By NIHR Maudsley BRC at 25 Jan 2021

COVID-19 lockdown loneliness linked to more depressive symptoms in older adults

Loneliness in adults aged 50 and over during the COVID-19 lockdown was linked to worsening depressive and other mental health symptoms, according to a large-scale online study.

By NIHR Maudsley BRC at 22 Jan 2021

NEWS2 evaluated for prediction of severe COVID-19 outcome in large international study

In the first systematic large-scale evaluation of the UK National Early Warning Risk Score (NEWS) 2 as a scoring system for predicting severe COVID-19 outcomes in patients, researchers at King’s College London have found poor-to-moderate accuracy for identifying patients at risk of being transferred to intensive care units (ICUs) or dying after 14 days of hospitalisation. Accuracy of predictions in short term (three days) showed moderate success.

 

By NIHR Maudsley BRC at 21 Jan 2021