The NIHR Maudsley Biomedical Research Centre (BRC) carries out translational research in mental health and neurology. Our aim is to accelerate the translation of the latest scientific discoveries into first-in-person clinical trials and other well-designed studies.
By bringing together scientists and clinicians from different disciplines, these findings can then be evaluated, developed and implemented in the NHS, providing new tests and treatments for people with mental health conditions and neurological disorders.
Research goals
Each of our 10 research themes is focused on delivering research configured around one or more of the research priorities or goals. The themes are defined by the area of diagnostic category or technological or methodological field and the focus on delivering research according the following priorities/goals:
1. Whole person care: to improve physical health outcomes in psychiatric disorders and mental health outcomes in physical disorders, to address the considerable excess mortality in psychiatric disorders and the impact of mental ill-health on physical health outcomes.
2. Translational Informatics: Using real-world data and advanced analytics capabilities to guide clinical care and public health, supported by our Informatics and Digital Therapies themes.
3. Precision Psychiatry and Neurology: To discover better targeted treatments by exploiting multimodal research data using neuroimaging, genomic, biomarker, cognitive, behavioural and remote-sensing data to identify intervention targets. This is sustained by methodology-orientated themes to provide unparalleled breadth and depth of phenotypic characterisation across disorders.
4. Novel preventive strategies and therapeutics: To develop innovative pharmacological, psychological, and digital interventions across disorders supported by our Experimental Medicine and Novel Therapeutics and Trials, Genomics and Prediction themes, to develop and test interventions.
Research outputs
Explore more detail about research outputs and researchers at the NIHR Maudsley Biomedical Research Centre on the King's College London Research Portal. It hosts a wide range of research information such as research outputs for individuals and research groups, funding details, as well as links to Open Access publications.
Visit the NIHR Maudsley BRC research unit page on King's Research Portal
Research themes 2022-2028
Research at the NIHR Maudsley BRC is organised into 10 themes:
Child Mental Health & Neurodevelopmental Disorders
We address mental health and neurodevelopmental conditions in childhood and adolescence.
Digital Therapies
We are accelerating the development, precision of, and implementation of novel digital therapeutics.
Eating Disorders and Obesity
We are developing our early interventions and new therapies to be tailored and scalable.
Experimental Medicine and Therapeutics
This theme is advancing experimental therapeutics with multiple endpoints.
Informatics
Our theme in informatics integrates rich clinical data with large datasets to better understand psychiatric disorders.
Motor Neuron Disease
This theme is evaluating new treatments and enabling drugs with potential to become available to patients.
Neuroimaging
We investigate brain structure, function, physiology and metabolism across psychiatric and neurological disorders.
Pain and Addictions
We use expertise from different specialities to enable a mind-body approach to lessening negative impacts in pain and addictions.
Psychosis and Mood Disorders
Our theme aims to transform the future of people suffering with psychosis and mood disorders.
Trials, Genomics and Prediction
We aim to deliver a step-change in patient-centred, data-driven mental health research at scale.
