I am Professor of Neurology and Complex Disease Genetics at the Maurice Wohl Clinical Neuroscience Institute, Head of the Department of Basic and Clinical Neuroscience, and Director of the King’s Motor Neuron Disease Research Centre. I trained in medicine in Leicester and London, and subsequently became a consultant neurologist at King’s College Hospital. My research focuses on amyotrophic lateral sclerosis, also known as ALS, MND or motor neuron disease. My research team works on finding the causes of ALS, and what might influence the way the disease manifests and progresses, particularly where this involves genes, environmental exposures, or lifestyle, or involves changes in thinking and coping. We run a large clinical research programme, including clinical trials.
Most science requires high levels of collaboration, and I lead or am involved in a large number of major EU and wider international projects in ALS, including STRENGTH, ALS-CarE, BRAIN-MEND, and Project MinE. I also sit on several international scientific advisory boards, and have held fellowships and exchange positions abroad including at Massachusetts General Hospital, Harvard University and Cold Spring Harbor Laboratory.
I set up our MSc in Clinical Neuroscience, our clinical research trainee programme, and have supervised many MSc students, PhD students and clinical and non-clinical fellows, several of them prize-winning. I have authored more than 250 peer-reviewed papers and hold extensive external grant funding, including 3 current and 6 recently completed programme grants, and funding from MRC, Horizon 2020, and NIHR.