Gloved hands using pipettes

BioResource


About us

The NIHR BioResource Centre Maudsley is part of the NIHR BioResource and works in collaboration with King’s College Hospital NHS Foundation Trust Neurological Services.  

The research tissue bank recruits participants living with, or without, mental health conditions. An important aspect of the biobank is that participants consent to being recontacted, thereby providing a valuable resource for the scientific community.

Specifically, we have volunteers with diagnoses of: 

  • dementia
  • schizophrenia
  • autism
  • mood disorders
  • eating disorders
  • Parkinson’s disorder
  • motor neuron disease
  • and neurological sleep and eye disorders.

We currently have over 15,000 volunteers with samples stored within the BioResource and are continuing to recruit volunteers. Additionally, we securely store patient contact details allowing us to re-approach our volunteers to help recruit for other studies and clinical trials.

Network of collaborators

We collaborate extensively with researchers and clinicians from: 

We support collaborating clinicians and welcome volunteers from our local communities and charitable organisations. We collaborate with existing research projects by organizing sample collections from participants, consenting them to our BioResource and then storing these for future use.

Online recruitment

The BioResource has pioneered large online projects, specifically the Genetic Links to Anxiety and Depression Study (GLAD Study) and the Eating Disorders Genetics Initiative UK (EDGI UK).

Both projects publicise the projects using standard social media platforms and have achieved huge success in not only recruiting large numbers of participating but also in educating the public about these conditions via weekly social media posts.

These projects are collecting extensive phenotypic data which has been valuable in researching aspects of these conditions.

EDGI, GLAD and IBHO logos

To find out more about our GLAD and EDGI projects, visit: 

The Genetic Links to Anxiety and Depression (GLAD) Study

  • led by the NIHR Mental Health BioResource and researchers at King’s College London, in collaboration with researchers at Ulster University, University of Edinburgh, and Cardiff University, is a project set up to support studies exploring risk factors for depression and/or anxiety.
  • Since it was launched in September 2018, approximately 56,000 participants had registered to the GLAD Study by March 2022.
  • The Study has successfully recruited almost 43,000 participants who have provided questionnaire data and of these, almost 30,000 participants have returned their saliva kits enabling us to do genetic analysis.
  • To date, the Study data and participants have been accessed by 50 researchers. Recruitment to the GLAD Study is also taking place via NHS sites and to date, 234 sites have been set up in NHS Trusts, GP practices and clinics. 

The Eating Disorders Genetics Initiative UK (EDGI)

  • also led by the NIHR Mental Health BioResource (part of the NIHR BioResource), researchers at King’s College London and Beat, the UK’s eating disorder charity, is a project set up to support studies exploring risk factors for eating disorders.
  • EDGI UK is part of a global effort to thoroughly investigate eating disorders, to investigate the inter-relationship between genes and environment and explore new therapies which may have more lasting effectiveness than current treatments.
  • Since its launch in February 2020, almost 12,000 participants have registered for the study and about 6,000 participants have completed the baseline questionnaire and almost 4,000 participants have provided saliva samples for DNA. EDGI UK has also been set up for recruitment in 10 NHS clinical sites.  

Recruiting Diverse Populations

We understand that individuals from many different ethnic minority communities are underrepresented in research studies, both as research participants and as researchers, and that this lack of representation has roots in historic injustice and systemic racism towards these groups.The NIHR BioResource Centre Maudsley is committed to prioritising this issue by engaging in discussions with different communities and taking necessary steps to improve representation in our team and our participants.

Improving Black Health Outcomes (IBHO) BioResource
The IBHO BioResource is a new research programme from the NIHR BioResource in collaboration with King's College London and Genomics England, focused on improving our knowledge and understanding of health conditions and their unique impacts on UK Black communities. It launched in September 2024.

We recognise that research involving genetics is especially sensitive and as such, we have a responsibility to be transparent about how we collect, analyse and store your data, as well as who has access to this.

For more information

Please contact Dr Gursharan Kalsi, Research Coordinator & Manager, SGDP Centre & Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), DeCrespigny Park, Denmark Hill, London SE5 8AF email: gursharan.kalsi@kcl.ac.uk for more information or to collaborate with the BioResource.

If you would like to volunteer for the BioResource, please email us at bioresource@kcl.ac.uk.

Take a look inside our biolab with Professor Gerome Breen (film from 2013):